Advanced Research Calcium Orotate is used to treat bone loss and pain due to inflammation or osteoporosis, psoriasis, high blood pressure, angina pectoris, multiple sclerosis, encephalitis, retinitis, hepatitis, and colitis.
 
Orotates are mineral salts of orotic acid used by plants and animals to make DNA and RNA. Hans Nieper, a physician and dabbler in offbeat theories of gravitation, used orotates clinically before 1980 until his death in 1998. He thought that orotate salts, being neutrally charged, pass easily through cell membranes. In effect, orotate ferries the mineral atoms into cells and tissues, producing higher concentrations.

Nieper promoted orotates as treatments for nearly every ailment imaginable and was consequently ignored; most of his medical claims were never rigorously tested. But in certain applications - such as athletic performance - where his ideas have recently received scientific scrutiny, they have been found to work. Nieper may have been on the right track after all.
 
Advanced Research brand nutritional supplements are the progression of Dr. Nieper's commitment to metabolic therapies in harmony with nature. Each Advanced Research brand has been designed to address specific needs metabolically; therefore, you can be assured that the Advanced Research brand represents one of the most advanced bio-available and results oriented nutritional products.
 
They painstakingly research each raw ingredient to assure that the highest potency most assimilable materials are used and that they meet Dr. Nieper’s standards of excellence. All Advanced Research products are then scientifically formulated and meticulously manufactured. Finally, each product is quality tested according to Dr. Nieper's Strict Specification. Only then is a product packaged, labeled and waiting to be shipped to you